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News and Updates

QART Medical Ltd. has received ethical committee approvals

QART Medical Ltd. has received ethical committee approvals to commence clinical studies in medical centres in Israel. QART Medical is an MedTech start-up, addressing the huge unmet need of male infertility.

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Qart Medical Ltd. receives Seal of Excellence from EU Horizon 2020

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QART Medical Ltd. has won the 3rd (monetary) prize in the 2020 from QCII

QART Medical Ltd. has won the 3rd (monetary) prize in the 2020 Qingdao High-tech Zone Lanebest International Innovation and Entrepreneurship Competition.

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QART receives second grant support from the Israeli Innovation Authority

QART’s R&D efforts are focused at bringing to IVF clinics worldwide a novel system called QISITM (Quantitative Interferometric Sperm Imager) – allowing the embryologist to make highly informed decisions, when selecting individual sperm cells for injection into the (female) egg in a dish, in a procedure called ICSI (intra-cytoplasmic sperm injection).

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QART Medical completes follow-on investment round

Raanana, Israel, September 2020; QART Medical completes follow-on investment round, led by Chartered Opus and joined by other existing, as well as new investors. Company was established to utilize advanced bio-photonics, to significantly improve the outcomes of ICSI (intra cytoplasmic sperm injection) treatments, a common type of IVF (in vitro fertilization) procedure, in which a single sperm cell is selected and manually injected into the female oocyte (i.e. egg).

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Hamamatsu joins Seed Financing of QART Medical

Hamamatsu Photonics K.K., has joined Chartered Investment Managers, a SEA-based investment management fund, the Tel Aviv University (T.A.U), Technology Innovation Momentum Fund, managed by Ramot, TAU’s Business Engagement Center and a group of angel investors, in the Seed financing round, having an initial closing on March 2019.

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QART Medical to Present in ECA 2018

QART Medical’s work on the assessment of DNA fragmentation of individual, unstained human sperm cells, has been accepted for presentation in the 10th Congress of the European Academy of Andrology (EAA). The congress will be held in Budapest, Hungary between October 11-13, 2018.

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Research on Stain-Free Sperm DNA Fragmentation Has Been Accepted for Publication

According to CDC’s 2016 Fertility Clinic Success Rates Report, there were 263,577 ART (assisted reproduction technology) cycles performed at 463 reporting clinics in the U.S during 2016, resulting in 65,996 live births, which is 1 out of 4 cycles (source: https://www.cdc.gov/art/artdata/index.html). Recent data consistently demonstrate a significant increase in miscarriage in patients with high DNA damage (i.e. fragmentation) compared with those with low DNA damage.

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QART Medical receives notice of EU allowance on patent covering its compact module

Q-ART Medical announces today that its European patent application, named "Portable Interferometric Device" to Shaked et al. has been allowed. The patent teaches the realization of a novel, simple to use, portable, compact and inexpensive platform for interferometric optical thickness measurements that can be easily incorporated into an existing microscopes with integrated cameras.

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Publications

1

M. Haifler, P. Girshovitz, G. Band, G. Dardikman, I. Madjar, and N. T. Shaked, “Interferometric phase microscopy for label-free morphological evaluation of sperm cells,” Fertility and Sterility, Vol. 104, Issue 1, pp. 43-47, 2015

2

M. Balberg, M. Levi, K. Kalinowski, I. Barnea, S. Mirsky, and N. T. Shaked, “Localized measurements of physical parameters within human sperm cells obtained with wide-field interferometry,” Journal of Biophotonics 10, 1305–1314, 2017

3

S. Mirsky, I. Barnea, and N. T. Shaked, “Label-free quantitative imaging of sperm for in-vitro fertilization using interferometric phase microscopy,” Journal of Fertilization: In Vitro, IVF – Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, 2016

4

P. Jacob Eravuchira, S. K. Mirsky, I. Barnea, M. Levi, M. Balberg, and N. T. Shaked, “Individual sperm selection by microfluidics integrated with interferometric phase microscopy,” Methods, Vol. 136, pp. 152-159, 2018

5

P. Girshovitz and N. T. Shaked, “Doubling the field of view in off-axis low-coherence interferometric imaging,” Nature – Light: Science and Applications (Nature LSA), Vol. 3, e151, pp. 1-9, 2014

6

P. Girshovitz and N. T. Shaked, “Compact and portable low-coherence interferometer with off-axis geometry for quantitative phase microscopy and nanoscopy,” Optics Express, Vol. 21, Issue 5, pp. 5701-5714, 2013

7

N. T. Shaked, “Quantitative phase microscopy of biological samples using a portable interferometer,” Optics Letters Vol. 37, No. 11, 2016-2019, 2012

8

P. Girshovitz and N. T. Shaked, “Fast phase processing in off-axis holography using multiplexing with complex encoding and live-cell fluctuation map calculation in real-time,” Optics Express, Vol. 23, Issue 7, pp. 8773-8787, 2015

9

P. Girshovitz and N. T. Shaked, “Real-time quantitative phase reconstruction in off-axis digital holography using multiplexing,” Optics Letters, Vol. 39, No. 8, 2262-2265, 2014

10

P. Girshovitz and N. T. Shaked, “Generalized cell morphological parameters based on interferometric phase microscopy and their application to cell life cycle characterization,” Biomedical Optics Express, Vol. 3, No. 8, pp. 1757-1773, 2012